Fa'ama'i Lima, Vae, ma le gutu (HFMD).
O le faama'i lima, vae ma le gutu e masani lava ona taatele i tamaiti laiti. E maualuga tele le pipisi, e iai le tele o fa'ama'i fa'ama'i e leai ni fa'aaliga, lavelave auala fe'avea'i, ma le sosolo vave, e ono fa'atupuina fa'atupu fa'ama'i i totonu o se taimi pu'upu'u, e fa'afaigata ai le puleaina o fa'ama'i. I taimi o fa'ama'i, e mafai ona tupu fa'ama'i fa'atasi i a'oa'oga ma nofoaga e tausi ai tamaiti, fa'apea fo'i ma fa'aputuga o fa'ama'i. I le 2008, na aofia ai le HFMD e le Matagaluega o le Soifua Maloloina i le puleaina o faʻamaʻi pipisi o le Category C.
Coxsackievirus A16 (CA16) ma le Enterovirus 71 (EV71) o fa'ama'i masani ia e mafua ai le HFMD. O fa'amaumauga fa'ama'i pipisi e fa'ailoa mai ai o le CA16 e masani ona fa'asalalau fa'atasi ma le EV71, e o'o atu ai i fa'ama'i so'o HFMD. I le taimi o nei faʻamaʻi, o le aofaʻi o faʻamaʻi pipisi o le CA16 e sili atu nai lo le EV71, e masani ona sili atu i le 60% o faʻamaʻi uma. O le HFMD e mafua mai i le EV71 e mafai ona o'o atu ai i le fa'aleagaina o le tino. O le fua faatatau o mataupu ogaoga ma le numera o maliu i tagata mamaʻi ua aʻafia i le EV71 e matua maualuga atu nai lo i latou na aʻafia i isi enterovirus, ma le ogaoga o faʻamaʻi pipisi e oʻo atu i le 10% -25%. Ae ui i lea, o le fa'ama'i o le CA16 e masani lava e le fa'atupuina fa'ama'i e feso'ota'i atu i le tino tutotonu e pei o le maningitis aseptic, fai'ai encephalitis, ma le poliomyelitis-pei o le pipili. O le mea lea, o su'esu'ega fa'avasegaina vave e taua tele mo le fa'asaoina o ola o fa'ama'i ogaoga.
Su'ega Falema'i
Ole su'esu'ega ile taimi nei mo le HFMD e aofia ai le su'esu'eina ole nucleic acid ole pathogen ma le su'esu'eina ole antibody serological. E fa'aogaina e le kamupani Beier le enzyme-linked immunosorbent assay (ELISA) ma le colloidal gold method e atia'e ai Enterovirus 71 Antibody Test Kits ma Coxsackievirus A16 IgM Antibody Test Kits mo le su'esu'eina o le eseesega o pathogens HFMD. O le su'esu'eina o le antibody serum e maua ai le maualuga, fa'apitoa lelei, ma e faigofie, vave, ma talafeagai mo su'esu'ega fa'afoma'i i totonu o fa'alapotopotoga fa'alesoifua maloloina i la'asaga uma ma mo su'esu'ega su'esu'ega fa'ama'i pipisi tele.
Fa'ailoga Fa'apitoa mo Su'esu'ega ma le Taua Fa'afoma'i ole Fa'ama'i EV71
Ole su'esu'ega fa'apitoa ole fa'ama'i EV71 e fa'alagolago ile su'esu'eina ole EV71-RNA, EV71-IgM, ma le EV71-IgG antibodies ile serum, po'o le mauaina ole EV71-RNA ile swab specimens.
I le mae'a ai o fa'ama'i EV71, o lo'o fa'aalia muamua fa'ama'i IgM, fa'ato'a maualuga ile vaiaso lona lua. IgG antibodies e amata ona aliali mai i le vaiaso lona lua pe a maeʻa faʻamaʻi ma tumau mo se taimi umi. EV71-IgM ose fa'ailoga taua ole fa'ama'i muamua po'o fa'ama'i lata mai, e fa'afaigofie ai ona vave iloa ma togafitia ole fa'ama'i EV71. EV71-IgG ose fa'ailoga autu mo le su'esu'eina o fa'ama'i fa'ama'i, aoga mo su'esu'ega fa'ama'i ma le iloiloga ole aoga ole tui. O le su'esu'eina o le suiga o le antibody titer i le va o fa'ata'ita'iga o le sua ma'i ma'i fa'amalologa e mafai fo'i ona iloa ai le tulaga fa'ama'i EV71; mo se fa'ata'ita'iga, e fa'afa pe sili atu fa'atupu fa'ateteleina o le antibody titer i le sua fa'amalolo pe a fa'atusatusa i le sua ma'i e mafai ona fa'amasinoina o se fa'ama'i EV71 o iai nei.
Fa'ailoga Fa'apitoa mo Su'esu'ega ma le Taua Fa'afoma'i ole Fa'ama'i CA16
Ole su'esu'ega fa'apitoa ole fa'ama'i o le CA16 e fa'alagolago ile su'esu'eina ole CA16-RNA, CA16-IgM, ma le CA16-IgG antibodies ile serum, po'o le mauaina ole CA16-RNA ile swab specimens.
A mae'a fa'ama'i CA16, e muamua fa'ailoa mai fa'ama'i IgM, fa'ato'a maualuga ile vaiaso lona lua. IgG antibodies e amata ona aliali mai i le vaiaso lona lua pe a maeʻa faʻamaʻi ma tumau mo se taimi umi. CA16-IgM ose fa'ailoga taua ole fa'ama'i muamua po'o fa'ama'i lata mai.
Taua ole Tu'ufa'atasi EV71 ma CA16 Su'ega Antibody
O le HFMD e mafua mai ile tele ole enterovirus, ma serotype masani ole EV71 ma le CA16. O su'esu'ega ua fa'ailoa mai ai o le HFMD e mafua mai i le virusi o le CA16 e masani lava ona maua mai fa'ailoga mata'utia, e itiiti fa'alavelave, ma e lelei fa'ama'i. I se fa'atusatusaga, o le HFMD e mafua mai i le EV71 e masani ona fa'aalia ai fa'ama'i ogaoga fa'ama'i, e maualuga atu le fua faatatau o mataupu ogaoga ma le oti, ma e masani ona feso'ota'i ma fa'alavelave fa'alavelave fa'alavelave. O fa'ailoga fa'apitoa ole HFMD e lavelave ma e masani ona leai se fa'ata'ita'iga, e fa'afaigata ai su'esu'ega ile falema'i, aemaise ile amataga. Ole taua ole su'esu'ega tu'ufa'atasi ole serum antibody o lo'o ta'oto ile sui ole faiga ole fa'ama'i fa'ama'i fa'ama'i fa'agata, fa'ailoa ile serologically ole pathogen, ma maua ai se fa'avae mo su'esu'ega ile falema'i, togafiti togafiti, ma fa'ama'i fa'ama'i.
Su'esu'ega o Galuega Fa'atino
EV71-IgM ELISAPusaIloiloga o Galuega
| Stele | No. omataupu | EV71-IgM Lelei | EV71-IgM Le lelei | Sfa'alogona | Sfa'apitoa |
| Fa'amaonia EV71 mataupu | 302 | 298 | 4 | 98.7% | —– |
| Ma'i Fa'ama'i E le-EV71 | 25 | 1 | 24 | —– | 96% |
| Tagata Lautele | 700 | —– | 700 | —– | 100% |
Fa'ailoa mai i'uga:O le Beier EV71-IgM Test Kit e fa'aalia ai le maualuga ma le fa'apitoa mo le su'eina o le sua mai tagata EV71-a'afia. Punaoa fa'amaumauga: National Institute for Viral Disease Control and Prevention, Saina CDC.
EV71-IgG ELISA Kit Su'esu'ega Fa'atinoga (I)
| Stele | No. omataupu | EV71-IgG Lelei | EV71-IgG Le lelei | Sfa'alogona | Sfa'apitoa |
| Fa'amaonia EV71 mataupu | 310 | 307 | 3 | 99.0% | —– |
| Ma'i Fa'ama'i E le-EV71 | 38 | 0 | 38 | —– | 100% |
| Tagata Lautele | 700 | 328 | 372 | —– | 100% |
EV71-IgG ELISA Kit Su'esu'ega Fa'atinoga (II)
| Stele | No. omataupu | EV71-IgG Lelei | EV71-IgG Le lelei | Sfa'alogona | Sfa'apitoa |
| O le faitau aofa'i o tagata, Su'ega Fa'aleaogaina lelei | 332 | 328 | 4 | 98.8% | —– |
| O le faitau aofa'i o tagata, Su'ega Fa'a'ese'ese Le lelei | 368 | —– | 368 | —– | 100% |
Fa'ailoa mai i'uga:O le Beier EV71-IgG Test Kit o lo'o fa'aalia ai le maualuga o le su'esu'eina o le sua mai tagata ta'ito'atasi o lo'o iai fa'ama'i EV71. Punaoa fa'amaumauga: National Institute for Viral Disease Control and Prevention, Saina CDC.
CA16-IgM ELISA Kit Su'esu'ega Fa'atinoga
| Stele | No. omataupu | CA16-IgM Lelei | CA16-IgM Le lelei | Sfa'alogona | Sfa'apitoa |
| Fa'amaonia mataupu CA16 | 350 | 336 | 14 | 96.0% | —– |
| Tagata Lautele | 659 | 0 | 659 | —– | 100% |
Fa'ailoa mai i'uga:O le Beier CA16-IgM Test Kit e fa'aalia ai le maualuga o le su'esu'ega ma le fetaui lelei. Punaoa fa'amaumauga: National Institute for Viral Disease Control and Prevention, Saina CDC.
EV71-IgM Su'ega Pusa (Colloidal Auro) Su'esu'ega Fa'atinoga
| Stele | No. omataupu | EV71-IgM Lelei | EV71-IgM Le lelei | Sfa'alogona | Sfa'apitoa |
| EV71-IgM Fa'ata'ita'iga Lelei | 90 | 88 | 2 | 97.8% | —– |
| Fa'ata'ita'iga Lelei a le PCR/Mata'i e le'o HFMD | 217 | 7 | 210 | —– | 96.8% |
Fa'ailoa mai i'uga:O le Beier EV71-IgM Test Kit (Colloidal Gold) o loʻo faʻaalia ai le maualuga ma le faʻamaonia lelei mo le suʻeina o le sua mai tagata EV71-aʻafia. Punaoa fa'amaumauga: National Institute for Viral Disease Control and Prevention, Saina CDC.
CA16-IgM Pusa Su'ega (Colloidal Auro) Su'esu'ega Fa'atinoga
| Stele | No. omataupu | CA16-IgM Lelei | CA16-IgM Le lelei | Sfa'alogona | Sfa'apitoa |
| CA16-IgM Fa'ata'ita'iga Lelei | 248 | 243 | 5 | 98.0% | —– |
| PCR fa'ata'ita'iga lelei / Mataupu e le o le HFMD | 325 | 11 | 314 | —– | 96.6% |
Fa'ailoa mai i'uga:O le Beier CA16-IgM Test Kit (Colloidal Gold) o loʻo faʻaalia ai le maualuga ma le faʻamaonia lelei mo le suʻeina o le toto mai tagata taʻitoʻatasi ua aʻafia i le CA16. Punaoa fa'amaumauga: National Institute for Viral Disease Control and Prevention, Saina CDC.
Taimi meli: Oke-30-2025